Diffuse Destructive Changes in the Liver Associated with Jaundice

Case 1.?M.S., female, 25, married, three children, youngest five months; pregnancy, confinement and puerperium natural. The illr.ess began on March 7th, 1906, with weakness and jaundice but no pain. The jaundice deepened, she vomited a few times and had a little pain in the back. On March 21st she came into the General Hospital under Dr. Parker. She was at that time deeply jaundiced, but with a clean tongue, a pulse of 100 and no fever. The edge of the liver was felt two inches below the costal border ; it was smooth and not tender. On March 23rd the pulse quickened to 156 ; she became delirious and died two days later in coma, with a temperature of 107?. At a post-mortem examination next day the tissues were deeply jaundiced, but not wasted or cedematous, and there was